| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TSNAX |
| Gene ID: | 7257 |
| Uniprot ID: | TSNAX_HUMAN |
| Immunogen Region: | 1-290 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human TSNAX (NP_005990.1). |
| Immunogen Sequence: | MSNKEGSGGFRKRKHDNFPH NQRREGKDVNSSSPVMLAFK SFQQELDARHDKYERLVKLS RDITVESKRTIFLLHRITSA PDMEDILTESEIKLDGVRQK IFQVAQELSGEDMHQFHRAI TTGLQEYVEAVSFQHFIKTR SLISMDEINKQLIFTTEDNG KENKTPSSDAQDKQFGTWRL RVTPVDYLLGVADLTGELMR MCINSVGNGDIDTPFEVSQF LRQVYDGFSFIGNTGPYEV |
| Post Translational Modifications | Sumoylated with SUMO1. |
| Function | Acts in combination with TSN as an endonuclease involved in the activation of the RNA-induced silencing complex (RISC). Possible role in spermatogenesis. |
| Protein Name | Translin-Associated Protein XTranslin-Associated Factor X |
| Database Links | Reactome: R-HSA-426486 |
| Cellular Localisation | CytoplasmPerinuclear RegionGolgi ApparatusNucleusAccumulate In The Golgi Complex Of Mid-Late Pachytene SpermatocytesExpressed In The Cytoplasm In The Presence Of Tsn |
| Alternative Antibody Names | Anti-Translin-Associated Protein X antibodyAnti-Translin-Associated Factor X antibodyAnti-TSNAX antibodyAnti-TRAX antibody |
Information sourced from Uniprot.org