| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TSLP |
| Gene ID: | 85480 |
| Uniprot ID: | TSLP_HUMAN |
| Immunogen Region: | 29-159 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-159 of human TSLP (NP_149024.1). |
| Immunogen Sequence: | YDFTNCDFEKIKAAYLSTIS KDLITYMSGTKSTEFNNTVS CSNRPHCLTEIQSLTFNPTA GCASLAKEMFAMKTKAALAI WCPGYSETQINATQAMKKRR KRKVTTNKCLEQVSQLQGLW RRFNRPLLKQQ |
| Tissue Specificity | Isoform 1 is expressed in a number of tissues including heart, liver and prostate. Isoform 2 is the predominant form in keratinocytes of oral mucosa, skin and in salivary glands. It is secreted into saliva. |
| Function | Isoform 1: Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells. Isoform 2: May act as an antimicrobial peptide in the oral cavity and on the skin. |
| Protein Name | Thymic Stromal Lymphopoietin |
| Database Links | Reactome: R-HSA-1266695 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Thymic Stromal Lymphopoietin antibodyAnti-TSLP antibody |
Information sourced from Uniprot.org