| Short Description : | Mouse monoclonal anti-Tryptase for use in IHC-p in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC-p |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | IHC678 |
| Conjugation: | Unconjugated |
| Formulation: | Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide |
| Storage Instruction: | Store at 2-8°C for up to 1 year. Do not freeze. |
| Specificity: | Tested and validated on ulterus tissue. |
| Background | Mast cell tryptase, also known simply as tryptase, is a highly abundant proteinase stored in basophils and the secretory granules of mast cells, which is released upon cellular activation. The enzyme is therefore considered a key marker for mast cell activation, as well as acting as a critical mediator of inflammation. Elevated levels of serum tryptase occur in both anaphylactic and anaphylactoid reactions. Anti-Tryptase acts as a good marker for mast cells, basophils, and their derivatives. |
Information sourced from Uniprot.org

