| Host: |
Sheep |
| Applications: |
IHC/WB |
| Reactivity: |
Human/Marmoset/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Sheep polyclonal antibody anti-TRPV2 is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Formulation: |
Lyophilised |
| Purification: |
Affinity purification |
| Dilution Range: |
IHC, WB. A dilution of 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: |
Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: |
TRPV2 |
| Gene ID: |
51393 |
| Uniprot ID: |
TRPV2_HUMAN |
| Specificity: |
Specific for TRPV2. |
| Immunogen: |
A synthetic peptide from human TRPV2 conjugated to blue carrier protein was used as the antigen. |
| Function | Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF1, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius.is not activated by vanilloids and acidic pH. |
| Protein Name | Transient Receptor Potential Cation Channel Subfamily V Member 2Trpv2Osm-9-Like Trp Channel 2Otrpc2Vanilloid Receptor-Like Protein 1Vrl-1 |
| Database Links | Reactome: R-HSA-3295583 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCytoplasmMelanosomeTranslocates From The Cytoplasm To The Plasma Membrane Upon Ligand StimulationIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Antibody Names | Anti-Transient Receptor Potential Cation Channel Subfamily V Member 2 antibodyAnti-Trpv2 antibodyAnti-Osm-9-Like Trp Channel 2 antibodyAnti-Otrpc2 antibodyAnti-Vanilloid Receptor-Like Protein 1 antibodyAnti-Vrl-1 antibodyAnti-TRPV2 antibodyAnti-VRL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
