| Host: |
Goat |
| Applications: |
Pep-ELISA/IHC |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-Trpc6-Mouse (Internal) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
IHC-5µg/mlELISA-antibody detection limit dilution 1:64000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_038866.2 |
| Immunogen Sequence: |
KQSSTRSSEDYHLNS |
| Post Translational Modifications | Phosphorylated by FYN, leading to an increase of TRPC6 channel activity. N-glycosylated. |
| Function | Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion. |
| Protein Name | Short Transient Receptor Potential Channel 6Trpc6Calcium Entry ChannelTransient Receptor Protein 6Trp-6 |
| Database Links | Reactome: R-MMU-114508Reactome: -MMU-139853Reactome: -MMU-3295583 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Short Transient Receptor Potential Channel 6 antibodyAnti-Trpc6 antibodyAnti-Calcium Entry Channel antibodyAnti-Transient Receptor Protein 6 antibodyAnti-Trp-6 antibodyAnti-Trpc6 antibodyAnti-Trp6 antibodyAnti-Trrp6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
