Western blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-TRPC5 antibody (828-878 aa) (STJ193753)

SKU:
STJ193753
£48.00 - £252.00
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Short transient receptor potential channel 5 (828-878 aa) is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TRPC5
Gene ID: 7224
Uniprot ID: TRPC5_HUMAN
Immunogen Region: 828-878 aa
Specificity: This antibody detects endogenous levels of TRPC5 at Human/Mouse
Immunogen: Synthesized peptide derived from the human TRPC5 at the amino acid range 828-878
Function Forms a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Has also been shown to be calcium-selective. May also be activated by intracellular calcium store depletion. Mediates calcium-dependent phosphatidylserine externalization and apoptosis in neurons via its association with PLSCR1. Acts on distinct neuronal populations in the hypothalamus to regulate innate behaviors including feeding, anxiety (flight/fight/fear), socialization, and maternal care.
Protein Name Short Transient Receptor Potential Channel 5
Trpc5
Transient Receptor Protein 5
Trp-5
Htrp-5
Htrp5
Database Links Reactome: R-HSA-3295583
Reactome: R-HSA-418890
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Short Transient Receptor Potential Channel 5 antibody
Anti-Trpc5 antibody
Anti-Transient Receptor Protein 5 antibody
Anti-Trp-5 antibody
Anti-Htrp-5 antibody
Anti-Htrp5 antibody
Anti-TRPC5 antibody
Anti-TRP5 antibody

Information sourced from Uniprot.org

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