| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-Short transient receptor potential channel 5 (828-878 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TRPC5 |
| Gene ID: | 7224 |
| Uniprot ID: | TRPC5_HUMAN |
| Immunogen Region: | 828-878 aa |
| Specificity: | This antibody detects endogenous levels of TRPC5 at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human TRPC5 at the amino acid range 828-878 |
| Function | Forms a receptor-activated non-selective calcium permeant cation channel. Mediates calcium-dependent phosphatidylserine externalization and apoptosis in neurons via its association with PLSCR1. Acts on distinct neuronal populations in the hypothalamus to regulate innate behaviors including feeding, anxiety (flight/fight/fear), socialization, and maternal care. |
| Protein Name | Short Transient Receptor Potential Channel 5Trpc5Transient Receptor Protein 5Trp-5Htrp-5Htrp5 |
| Database Links | Reactome: R-HSA-3295583Reactome: R-HSA-418890 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Short Transient Receptor Potential Channel 5 antibodyAnti-Trpc5 antibodyAnti-Transient Receptor Protein 5 antibodyAnti-Trp-5 antibodyAnti-Htrp-5 antibodyAnti-Htrp5 antibodyAnti-TRPC5 antibodyAnti-TRP5 antibody |
Information sourced from Uniprot.org
