Anti-Trop-2/TACSTD2 antibody (ECD) [M005] (STJA0041415)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenClone M005 was generated from a proprietary antigen related to the extracellular region of human Trop-2 from the A431 epidermoid carcinoma cell line.
General Information
| Short Description | Mouse monoclonal anti-Trop-2/TACSTD2 (ECD) for use in ELISA, WB, ICC and IP in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB/ICC/IP |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | M005 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Purification | Protein G Purified |
| Dilution Range | WB 1:1000ICC 1:100IP 1:100 |
| Formulation | PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol |
| Storage Instruction | Storage at-20ยฐC is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at-20ยฐC. |
Target Information
| Gene Symbol | TACSTD2 |
| Gene ID | 4070 |
| Uniprot ID | TACD2_HUMAN |
| Immunogen | Clone M005 was generated from a proprietary antigen related to the extracellular region of human Trop-2 from the A431 epidermoid carcinoma cell line. |
| Immunogen Region | ECD |
| Immunogen Sequence | Human |
| Specificity | Clone M005 detects a 50-65 kDa* band corresponding to the molecular mass of Trop-2 on SDS-PAGE immunoblots of native human A431, MDA-MB-231, and MCF-7 cell lysates. The antibody also detects denatured Trop-2, but with less affinity. Lower dilutions o |
Additional Info
| Tissue Specificity | Placenta, pancreatic carcinoma cell lines. |
| Post Translational Modifications | The N-terminus is blocked. |
| Function | May function as a growth factor receptor. |
| Protein Name | Tumor-Associated Calcium Signal Transducer 2Cell Surface Glycoprotein Trop-2Membrane Component Chromosome 1 Surface Marker 1Pancreatic Carcinoma Marker Protein Ga733-1 |
| Database Links | |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Tumor-Associated Calcium Signal Transducer 2 antibodyAnti-Cell Surface Glycoprotein Trop-2 antibodyAnti-Membrane Component Chromosome 1 Surface Marker 1 antibodyAnti-Pancreatic Carcinoma Marker Protein Ga733-1 antibodyAnti-TACSTD2 antibodyAnti-GA733-1 antibodyAnti-M1S1 antibodyAnti-TROP2 antibody |
Information sourced from Uniprot.org