• Western blot analysis of lysates from MCF-7 cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-TRMT6 antibody (175-225 aa) (STJ195314)

SKU:
STJ195314

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-tRNA-N1-methyltransferase non-catalytic subunit TRM6-methyltransferase non-catalytic subunit TRM6-methyltransferase subunit TRM6MTase subunit TRM6 (175-225 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TRMT6
Gene ID: 51605
Uniprot ID: TRM6_HUMAN
Immunogen Region: 175-225 aa
Specificity: This antibody detects endogenous levels of TRM6 at Human/Mouse
Immunogen: Synthesized peptide derived from the human TRM6 at the amino acid range 175-225
Function Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. Together with the TRMT61A catalytic subunit, part of a mRNA N(1)-methyltransferase complex that mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs: N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries.
Protein Name Trna
Adenine(58-N(1-Methyltransferase Non-Catalytic Subunit Trm6
Mrna Methyladenosine-N(1-Methyltransferase Non-Catalytic Subunit Trm6
Trna(M1a58-Methyltransferase Subunit Trm6
Trna(M1a58mtase Subunit Trm6
Database Links Reactome: R-HSA-6782315
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Trna antibody
Anti-Adenine(58-N(1-Methyltransferase Non-Catalytic Subunit Trm6 antibody
Anti-Mrna Methyladenosine-N(1-Methyltransferase Non-Catalytic Subunit Trm6 antibody
Anti-Trna(M1a58-Methyltransferase Subunit Trm6 antibody
Anti-Trna(M1a58mtase Subunit Trm6 antibody
Anti-TRMT6 antibody
Anti-KIAA1153 antibody
Anti-TRM6 antibody
Anti-CGI-09 antibody

Information sourced from Uniprot.org

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