Post Translational Modifications | Phosphorylation at Tyr-55 by SRC is required for enhancement of lysophosphatidic acid-induced cell migration. Tyr-55 is dephosphorylated by PTPN13. |
Function | Relays signals from the cell surface to the nucleus to weaken adherens junction and promote actin cytoskeleton reorganization and cell invasiveness. Involved in lysophosphatidic acid-induced cell adhesion and migration. Acts as a transcriptional coactivator for NF-kappa-B and JUN, and mediates the transrepression of these transcription factors induced by glucocorticoid receptor. |
Protein Name | Thyroid Receptor-Interacting Protein 6Tr-Interacting Protein 6Trip-6Opa-Interacting Protein 1Oip-1Zyxin-Related Protein 1Zrp-1 |
Cellular Localisation | CytoplasmCytoskeletonCell JunctionFocal AdhesionNucleusShuttles Between Nucleus And CytoplasmColocalizes With Actin |
Alternative Antibody Names | Anti-Thyroid Receptor-Interacting Protein 6 antibodyAnti-Tr-Interacting Protein 6 antibodyAnti-Trip-6 antibodyAnti-Opa-Interacting Protein 1 antibodyAnti-Oip-1 antibodyAnti-Zyxin-Related Protein 1 antibodyAnti-Zrp-1 antibodyAnti-TRIP6 antibodyAnti-OIP1 antibody |
Information sourced from Uniprot.org