Anti-TRIP13 antibody [2F5] (STJA0032748)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenPurified recombinant human TRIP13 protein fragments expressed in E.coli.
General Information
| Short Description | Mouse monoclonal anti-TRIP13 for use in WB and IHC-P in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P |
| Host | Mouse |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 2F5 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100 |
| Formulation | Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | TRIP13 |
| Gene ID | 9319 |
| Uniprot ID | PCH2_HUMAN |
| Immunogen | Purified recombinant human TRIP13 protein fragments expressed in E.coli. |
Additional Info
| Function | Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes. Plays a role in mitotic spindle assembly checkpoint (SAC) activation. |
| Protein Name | Pachytene Checkpoint Protein 2 HomologHuman Papillomavirus Type 16 E1 Protein-Binding Protein16e1-BpHpv16 E1 Protein-Binding ProteinThyroid Hormone Receptor Interactor 13Thyroid Receptor-Interacting Protein 13Tr-Interacting Protein 13Trip-13 |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Pachytene Checkpoint Protein 2 Homolog antibodyAnti-Human Papillomavirus Type 16 E1 Protein-Binding Protein antibodyAnti-16e1-Bp antibodyAnti-Hpv16 E1 Protein-Binding Protein antibodyAnti-Thyroid Hormone Receptor Interactor 13 antibodyAnti-Thyroid Receptor-Interacting Protein 13 antibodyAnti-Tr-Interacting Protein 13 antibodyAnti-Trip-13 antibodyAnti-TRIP13 antibodyAnti-PCH2 antibody |
Information sourced from Uniprot.org