| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TRIM66 |
| Gene ID: | 9866 |
| Uniprot ID: | TRI66_HUMAN |
| Immunogen Region: | 750-970 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 750-970 of human TRIM66 (NP_055633.1). |
| Immunogen Sequence: | LATCPLQSIPPVSDMQPETG SSSSSGRTSGSLCPRDGADP SLENALCKVKLEEPINLSVK KPPLAPVVSTSTALQQYQNP KECENFEQGALELDAKENQS IRAFNSEHKIPYVRLERLKI CAASSGEMPVFKLKPQKNDQ DGSFLLIIECGTESSSMSIK VSQDRLSEATQAPGLEGRKV TVTSLAGQRPPEVEGTSPEE HRLIPRTPGAKKGPPAPIEN E |
| Function | May function as transcription repressor.The repressive effects are mediated, at least in part, by recruitment of deacetylase activity. May play a role as negative regulator of postmeiotic genes acting through CBX3 complex formation and centromere association. |
| Protein Name | Tripartite Motif-Containing Protein 66 |
| Cellular Localisation | NucleusForms Discrete Foci Within The Centromeric Chromocenter And Surrounding Nucleoplasm |
| Alternative Antibody Names | Anti-Tripartite Motif-Containing Protein 66 antibodyAnti-TRIM66 antibodyAnti-C11orf29 antibodyAnti-KIAA0298 antibody |
Information sourced from Uniprot.org