Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-TRIM66 (750-970) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
TRIM66 |
Gene ID: |
9866 |
Uniprot ID: |
TRI66_HUMAN |
Immunogen Region: |
750-970 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 750-970 of human TRIM66 (NP_055633.1). |
Immunogen Sequence: |
LATCPLQSIPPVSDMQPETG SSSSSGRTSGSLCPRDGADP SLENALCKVKLEEPINLSVK KPPLAPVVSTSTALQQYQNP KECENFEQGALELDAKENQS IRAFNSEHKIPYVRLERLKI CAASSGEMPVFKLKPQKNDQ DGSFLLIIECGTESSSMSIK VSQDRLSEATQAPGLEGRKV TVTSLAGQRPPEVEGTSPEE HRLIPRTPGAKKGPPAPIEN E |
Function | May function as transcription repressor.The repressive effects are mediated, at least in part, by recruitment of deacetylase activity. May play a role as negative regulator of postmeiotic genes acting through CBX3 complex formation and centromere association. |
Protein Name | Tripartite Motif-Containing Protein 66 |
Cellular Localisation | NucleusForms Discrete Foci Within The Centromeric Chromocenter And Surrounding Nucleoplasm |
Alternative Antibody Names | Anti-Tripartite Motif-Containing Protein 66 antibodyAnti-TRIM66 antibodyAnti-C11orf29 antibodyAnti-KIAA0298 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance