| Host: | Rabbit |
| Applications: | WB/IHC-P |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal anti-Transferrin Receptor 2 for use in WB and IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | R04-7T7 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification: | Affinity Chromatography |
| Dilution Range: | WB 1:500-1:1000IHC 1:50-1:100 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | TFR2 |
| Gene ID: | 7036 |
| Uniprot ID: | TFR2_HUMAN |
| Immunogen: | A synthesized peptide derived from human Transferrin Receptor 2 |
| Tissue Specificity | Predominantly expressed in liver. While the alpha form is also expressed in spleen, lung, muscle, prostate and peripheral blood mononuclear cells, the beta form is expressed in all tissues tested, albeit weakly. |
| Function | Mediates cellular uptake of transferrin-bound iron in a non-iron dependent manner. May be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. |
| Protein Name | Transferrin Receptor Protein 2Tfr2 |
| Database Links | Reactome: R-HSA-917977 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinIsoform Beta: CytoplasmLacks The Transmembrane DomainProbably Intracellular |
| Alternative Antibody Names | Anti-Transferrin Receptor Protein 2 antibodyAnti-Tfr2 antibodyAnti-TFR2 antibody |
Information sourced from Uniprot.org