| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TPP2 |
| Gene ID: | 7174 |
| Uniprot ID: | TPP2_HUMAN |
| Immunogen Region: | 1-300 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human TPP2 (NP_003282.2). |
| Immunogen Sequence: | MATAATEEPFPFHGLLPKKE TGAASFLCRYPEYDGRGVLI AVLDTGVDPGAPGMQVTTDG KPKIVDIIDTTGSGDVNTAT EVEPKDGEIVGLSGRVLKIP ASWTNPSGKYHIGIKNGYDF YPKALKERIQKERKEKIWDP VHRVALAEACRKQEEFDVAN NGSSQANKLIKEELQSQVEL LNSFEKKYSDPGPVYDCLVW HDGEVWRACIDSNEDGDLSK STVLRNYKEAQEYGSFGTA |
| Function | Cytosolic tripeptidyl-peptidase that releases N-terminal tripeptides from polypeptides and is a component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway. It plays an important role in intracellular amino acid homeostasis. Stimulates adipogenesis. |
| Protein Name | Tripeptidyl-Peptidase 2Tpp-2Tripeptidyl AminopeptidaseTripeptidyl-Peptidase IiTpp-Ii |
| Database Links | Reactome: R-HSA-983168 |
| Cellular Localisation | CytoplasmNucleusTranslocates To The Nucleus In Response To Gamma-Irradiation |
| Alternative Antibody Names | Anti-Tripeptidyl-Peptidase 2 antibodyAnti-Tpp-2 antibodyAnti-Tripeptidyl Aminopeptidase antibodyAnti-Tripeptidyl-Peptidase Ii antibodyAnti-Tpp-Ii antibodyAnti-TPP2 antibody |
Information sourced from Uniprot.org