| Short Description : | Mouse monoclonal anti-Thyroid peroxidase (600-700 aa) for use in IHC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC/IF |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | ABT-TPO |
| Isotype: | IgG2bk |
| Conjugation: | Unconjugated |
| Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range: | IHC-P 1:100-500IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TPO |
| Gene ID: | 7173 |
| Uniprot ID: | PERT_HUMAN |
| Immunogen: | Synthesized peptide derived from the human Thyroid Peroxidase (TPO) at the amino acid range 600-700 |
| Immunogen Region: | 600-700 aa |
| Specificity: | This antibody detects endogenous levels of human Thyroid Peroxidase (TPO). Heat-induced epitope retrieval (HIER) Citrate buffer of pH6.0 was highly recommended as antigen repair method in paraffin sec |
| Function | Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4). |
| Protein Name | Thyroid PeroxidaseTpo |
| Database Links | Reactome: R-HSA-209968 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinIsoform 3: Cell Surface |
| Alternative Antibody Names | Anti-Thyroid Peroxidase antibodyAnti-Tpo antibodyAnti-TPO antibody |
Information sourced from Uniprot.org
