• Immunohistochemistry analysis of paraffin-embedded rat thyroid using Thyroid Peroxidase Rabbit monoclonal antibody (STJ11103933) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9. 0 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded mouse thyroid using Thyroid Peroxidase Rabbit monoclonal antibody (STJ11103933) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9. 0 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded human thyroid cancer using Thyroid Peroxidase Rabbit monoclonal antibody (STJ11103933) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9. 0 before commencing with immunohistochemistry staining protocol.

Anti-TPO antibody (1-100) [S3933RM] (STJ11103933)

SKU:
STJ11103933

£146.50 - £639.50
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Host: Rabbit
Applications: IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-Thyroid Peroxidase (1-100) is suitable for use in Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: S3933RM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TPO
Gene ID: 7173
Uniprot ID: PERT_HUMAN
Immunogen Region: 1-100
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Thyroid Peroxidase (P07202).
Immunogen Sequence: MRALAVLSVTLVMACTEAFF PFISRGKELLWGKPEESRVS SVLEESKRLVDTAMYATMQR NLKKRGILSPAQLLSFSKLP EPTSGVIARAAEIMETSIQA
Post Translational Modifications Glycosylated. Heme is covalently bound through a H(2)O(2)-dependent autocatalytic process. Heme insertion is important for the delivery of protein at the cell surface. Cleaved in its N-terminal part.
Function Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4).
Protein Name Thyroid Peroxidase
Tpo
Database Links Reactome: R-HSA-209968
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Isoform 3: Cell Surface
Alternative Antibody Names Anti-Thyroid Peroxidase antibody
Anti-Tpo antibody
Anti-TPO antibody

Information sourced from Uniprot.org

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