| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Thiamin pyrophosphokinase 1 (171-221) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:1000-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TPK1 |
| Gene ID: |
27010 |
| Uniprot ID: |
TPK1_HUMAN |
| Immunogen Region: |
171-221 |
| Specificity: |
This antibody detects endogenous levels of human TPK1 |
| Immunogen: |
Synthesized peptide derived from human TPK1 AA range: 171-221 |
| Function | Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate (TPP) utilizing UTP and therefore links the biosynthesis of TPP to pyrimidines metabolism. By producing thiamine pyrophosphate, a cofactor of the mitochondrial pyruvate dehydrogenase indirectly regulates pyruvate oxidation and lipogenesis. Although it can also catalyze thiamine phosphorylation using ATP and CTP in vitro, it does so with significantly lower efficiency and without physiological relevance evidence. |
| Protein Name | Thiamine Pyrophosphokinase 1Htpk1Placental Protein 20Pp20Thiamin Pyrophosphokinase 1 |
| Database Links | Reactome: R-HSA-196819 |
| Alternative Antibody Names | Anti-Thiamine Pyrophosphokinase 1 antibodyAnti-Htpk1 antibodyAnti-Placental Protein 20 antibodyAnti-Pp20 antibodyAnti-Thiamin Pyrophosphokinase 1 antibodyAnti-TPK1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
