| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TNP2 (1-138) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TNP2 |
| Gene ID: |
7142 |
| Uniprot ID: |
STP2_HUMAN |
| Immunogen Region: |
1-138 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-138 of human TNP2 (NP_005416.1). |
| Immunogen Sequence: |
MDTQTHSLPITHTQLHSNSQ PQSRTCTRHCQTFSQSCRQS HRGSRSQSSSQSPASHRNPT GAHSSSGHQSQSPNTSPPPK RHKKTMNSHHSPMRPTILHC RCPKNRKNLEGKLKKKKMAK RIQQVYKTKTRSSGWKSN |
| Tissue Specificity | Expressed by spermatids (at protein level). |
| Function | Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. |
| Protein Name | Nuclear Transition Protein 2Tp-2Tp2 |
| Cellular Localisation | NucleusNucleolusChromosomeLoaded Onto The Nucleosomes Of Condensing SpermatidsNuclear Import Is Mediated By Ipo4Nucleolar Localization Requires The Protein To Be Phosphorylated |
| Alternative Antibody Names | Anti-Nuclear Transition Protein 2 antibodyAnti-Tp-2 antibodyAnti-Tp2 antibodyAnti-TNP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
