Anti-TNKS1BP1 antibody (700-1000) (STJ11103972)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal 182 Kda Tankyrase-1-Binding Protein (700-1000) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TNKS1BP1 |
| Gene ID | 85456 |
| Uniprot ID | TB182_HUMAN |
| Immunogen Region | 700-1000 |
| Immunogen Sequence | RRGAGAELKDTQSPSTCSEG LLGWSQKDLQSEFGITGDPQ PSSFSPSSWCQGASQDYGLG GASPRGDPGLGERDWTSKYG QGAGEGSTREWASRCGIGQE EMEASSSQDQSKVSAPGVLT AQDRVVGKPAQLGTQRSQEA DVQDWEFRKRDSQGTYSSRD AELQDQEFGKRDSLGTYSSR DVSLGDWEFGKRDSLGAYAS QDANEQGQDLGKRDHHGRYS SQDADEQDWEFQKRDVSLG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 700-1000 of human TNKS1BP1 (NP_203754.2). |
Additional Info
| Tissue Specificity | Detected in testis, ovary, lung, skeletal muscle, heart, prostate and pancreas, and at very low levels in brain and peripheral blood leukocytes. |
| Post Translational Modifications | ADP-ribosylated by TNKS1 (in vitro). |
| Protein Name | 182 Kda Tankyrase-1-Binding Protein |
| Database Links | Reactome: R-HSA-429947Reactome: R-HSA-6804115Reactome: R-HSA-9820841 |
| Cellular Localisation | NucleusCytoplasmCytoskeletonChromosomeColocalizes With Chromosomes During MitosisAnd In The Cytoplasm With Cortical Actin |
| Alternative Antibody Names | Anti-182 Kda Tankyrase-1-Binding Protein antibodyAnti-TNKS1BP1 antibodyAnti-KIAA1741 antibodyAnti-TAB182 antibody |
Information sourced from Uniprot.org