Anti-TNK1 antibody (451-560 aa) [1B5G3/3F11H6] (STJ98425)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenPurified recombinant fragment of TNK1 (aa451-560) expressed in E. Coli.
General Information
| Short Description | Mouse monoclonal anti-Non-receptor tyrosine-protein kinase TNK1 (451-560 aa) for use in WB and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 1B5G3/3F11H6 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Dilution Range | WB 1:500-1:2000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TNK1 |
| Gene ID | 8711 |
| Uniprot ID | TNK1_HUMAN |
| Immunogen | Purified recombinant fragment of TNK1 (aa451-560) expressed in E. Coli. |
| Immunogen Region | 451-560 aa |
| Specificity | TNK1 Monoclonal Antibody detects endogenous levels of TNK1 protein. |
Additional Info
| Post Translational Modifications | Autophosphorylated on tyrosine residues. |
| Function | Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in phospholipid signal transduction. |
| Protein Name | Non-Receptor Tyrosine-Protein Kinase Tnk1Cd38 Negative Kinase 1 |
| Database Links | |
| Cellular Localisation | CytoplasmMembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Non-Receptor Tyrosine-Protein Kinase Tnk1 antibodyAnti-Cd38 Negative Kinase 1 antibodyAnti-TNK1 antibody |
Information sourced from Uniprot.org