| Short Description : | Rabbit polyclonal anti-TNFAIP3-interacting protein 3 (40-120 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TNIP3 |
| Gene ID: | 79931 |
| Uniprot ID: | TNIP3_HUMAN |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 40-120 |
| Immunogen Region: | 40-120 aa |
| Specificity: | TNIP3 Polyclonal Antibody detects endogenous levels of protein. |
| Function | Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding. |
| Protein Name | Tnfaip3-Interacting Protein 3A20-Binding Inhibitor Of Nf-Kappa-B Activation 3Abin-3Listeria-Induced Gene Protein |
| Database Links | Reactome: R-HSA-5689896 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Tnfaip3-Interacting Protein 3 antibodyAnti-A20-Binding Inhibitor Of Nf-Kappa-B Activation 3 antibodyAnti-Abin-3 antibodyAnti-Listeria-Induced Gene Protein antibodyAnti-TNIP3 antibodyAnti-ABIN3 antibodyAnti-LIND antibody |
Information sourced from Uniprot.org
