| Host: | Rabbit |
| Applications: | WB/IHC |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Tumor necrosis factor ligand superfamily member 14 (51-100 aa) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 IHC-P 1:50-300 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TNFSF14 |
| Gene ID: | 8740 |
| Uniprot ID: | TNF14_HUMAN |
| Immunogen Region: | 51-100 aa |
| Specificity: | LIGHT Polyclonal Antibody detects endogenous levels of LIGHT protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human TNF14 at the amino acid range 51-100 |
| Post Translational Modifications | N-glycosylated. The soluble form of isoform 1 derives from the membrane form by proteolytic processing. |
| Function | Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Acts as a ligand for TNFRSF14/HVEM. Upon binding to TNFRSF14/HVEM, delivers costimulatory signals to T cells, leading to T cell proliferation and IFNG production. |
| Protein Name | Tumor Necrosis Factor Ligand Superfamily Member 14 Herpes Virus Entry Mediator Ligand Hvem-L Herpesvirus Entry Mediator Ligand Cd Antigen Cd258 Cleaved Into - Tumor Necrosis Factor Ligand Superfamily Member 14 - Membrane Form - Tumor Necrosis Factor Ligand Superfamily Member 14 - Soluble Form |
| Database Links | Reactome: R-HSA-5668541 Reactome: R-HSA-5669034 Reactome: R-HSA-5676594 |
| Cellular Localisation | Tumor Necrosis Factor Ligand Superfamily Member 14 Membrane Form: Cell Membrane Single-Pass Type Ii Membrane Protein Soluble Form: Secreted Isoform 2: Cytoplasm |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Ligand Superfamily Member 14 antibody Anti-Herpes Virus Entry Mediator Ligand antibody Anti-Hvem-L antibody Anti-Herpesvirus Entry Mediator Ligand antibody Anti-Cd Antigen Cd258 Cleaved Into - Tumor Necrosis Factor Ligand Superfamily Member 14 - Membrane Form - Tumor Necrosis Factor Ligand Superfamily Member 14 - Soluble Form antibody Anti-TNFSF14 antibody Anti-HVEML antibody Anti-LIGHT antibody Anti-UNQ391 antibody Anti-PRO726 antibody |
Information sourced from Uniprot.org