Western blot analysis of the lysates from HeLa cells using TNF12 antibody.

Anti-TNFSF12 antibody (41-90 aa) (STJ96150)

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STJ96150
£48.00 - £252.00
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Tumor necrosis factor ligand superfamily member 12 (41-90 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TNFSF12
Gene ID: 407977/8742
Uniprot ID: TNF12_HUMAN
Immunogen Region: 41-90 aa
Specificity: TWEAK Polyclonal Antibody detects endogenous levels of TWEAK protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human TNFSF12 at the amino acid range 41-90
Post Translational Modifications The soluble form derives from the membrane form by proteolytic processing.
Function Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.
Protein Name Tumor Necrosis Factor Ligand Superfamily Member 12
Apo3 Ligand
Tnf-Related Weak Inducer Of Apoptosis
Tweak Cleaved Into - Tumor Necrosis Factor Ligand Superfamily Member 12 - Membrane Form - Tumor Necrosis Factor Ligand Superfamily Member 12 - Secreted Form
Database Links Reactome: R-HSA-5668541
Reactome: R-HSA-5676594
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Tumor Necrosis Factor Ligand Superfamily Member 12
Secreted Form: Secreted
Isoform Twe-Pril: Cell Membrane
Single-Pass Membrane Protein
Alternative Antibody Names Anti-Tumor Necrosis Factor Ligand Superfamily Member 12 antibody
Anti-Apo3 Ligand antibody
Anti-Tnf-Related Weak Inducer Of Apoptosis antibody
Anti-Tweak Cleaved Into - Tumor Necrosis Factor Ligand Superfamily Member 12 - Membrane Form - Tumor Necrosis Factor Ligand Superfamily Member 12 - Secreted Form antibody
Anti-TNFSF12 antibody
Anti-APO3L antibody
Anti-DR3LG antibody
Anti-UNQ181 antibody
Anti-PRO207 antibody

Information sourced from Uniprot.org

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