| Host: |
Rabbit |
| Applications: |
WB/IF/ICC/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TNFRSF25 |
| Gene ID: |
8718 |
| Uniprot ID: |
TNR25_HUMAN |
| Immunogen Region: |
25-190 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 25-190 of human TNFRSF25 (NP_683866.1). |
| Immunogen Sequence: |
QGGTRSPRCDCAGDFHKKIG LFCCRGCPAGHYLKAPCTEP CGNSTCLVCPQDTFLAWENH HNSECARCQACDEQASQVAL ENCSAVADTRCGCKPGWFVE CQVSQCVSSSPFYCQPCLDC GALHRHTRLLCSRRDTDCGT CLPGFYEHGDGCVSCPTPPP SLAGAP |
| Tissue Specificity | Abundantly expressed in thymocytes and lymphocytes. Detected in lymphocyte-rich tissues such as thymus, colon, intestine, and spleen. Also found in the prostate. |
| Post Translational Modifications | (Microbial infection) Glycosylated at Arg-352 by enteropathogenic E.coli protein NleB1. Glycosylated. |
| Function | Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 25Apo-3Apoptosis-Inducing Receptor AirApoptosis-Mediating Receptor Dr3Apoptosis-Mediating Receptor TrampDeath Receptor 3Lymphocyte-Associated Receptor Of DeathLardProtein WslProtein Wsl-1 |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Cell MembraneIsoform 9: Cell MembraneIsoform 11: Cell MembraneIsoform 3: SecretedIsoform 4: SecretedIsoform 5: SecretedIsoform 6: SecretedIsoform 7: SecretedIsoform 8: SecretedIsoform 10: SecretedIsoform 12: Secreted |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 25 antibodyAnti-Apo-3 antibodyAnti-Apoptosis-Inducing Receptor Air antibodyAnti-Apoptosis-Mediating Receptor Dr3 antibodyAnti-Apoptosis-Mediating Receptor Tramp antibodyAnti-Death Receptor 3 antibodyAnti-Lymphocyte-Associated Receptor Of Death antibodyAnti-Lard antibodyAnti-Protein Wsl antibodyAnti-Protein Wsl-1 antibodyAnti-TNFRSF25 antibodyAnti-APO3 antibodyAnti-DDR3 antibodyAnti-DR3 antibodyAnti-TNFRSF12 antibodyAnti-WSL antibodyAnti-WSL1 antibodyAnti-UNQ455 antibodyAnti-PRO779 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
