| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TNFRSF12A (28-129) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TNFRSF12A |
| Gene ID: |
51330 |
| Uniprot ID: |
TNR12_HUMAN |
| Immunogen Region: |
28-129 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 28-129 of human TWEAKR/Fn14/CD266 (NP_057723.1). |
| Immunogen Sequence: |
EQAPGTAPCSRGSSWSADLD KCMDCASCRARPHSDFCLGC AAAPPAPFRLLWPILGGALS LTFVLGLLSGFLVWRRCRRR EKFTTPIEETGGEGCPAVAL IQ |
| Tissue Specificity | Highly expressed in heart, placenta and kidney. Intermediate expression in lung, skeletal muscle and pancreas. |
| Function | Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 12aFibroblast Growth Factor-Inducible Immediate-Early Response Protein 14Fgf-Inducible 14Tweak-ReceptorTweakrCd Antigen Cd266 |
| Database Links | Reactome: R-HSA-5668541Reactome: R-HSA-5676594 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 12a antibodyAnti-Fibroblast Growth Factor-Inducible Immediate-Early Response Protein 14 antibodyAnti-Fgf-Inducible 14 antibodyAnti-Tweak-Receptor antibodyAnti-Tweakr antibodyAnti-Cd Antigen Cd266 antibodyAnti-TNFRSF12A antibodyAnti-FN14 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
