Western blot analysis of lysates from HT-1080 cells, using TWEAKR/Fn14/CD266 Rabbit polyclonal antibody (STJ115060) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-TNFRSF12A antibody (28-129) (STJ115060)

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STJ115060
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TNFRSF12A
Gene ID: 51330
Uniprot ID: TNR12_HUMAN
Immunogen Region: 28-129
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 28-129 of human TWEAKR/Fn14/CD266 (NP_057723.1).
Immunogen Sequence: EQAPGTAPCSRGSSWSADLD KCMDCASCRARPHSDFCLGC AAAPPAPFRLLWPILGGALS LTFVLGLLSGFLVWRRCRRR EKFTTPIEETGGEGCPAVAL IQ
Tissue Specificity Highly expressed in heart, placenta and kidney. Intermediate expression in lung, skeletal muscle and pancreas.
Function Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 12a
Fibroblast Growth Factor-Inducible Immediate-Early Response Protein 14
Fgf-Inducible 14
Tweak-Receptor
Tweakr
Cd Antigen Cd266
Database Links Reactome: R-HSA-5668541
Reactome: R-HSA-5676594
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Tumor Necrosis Factor Receptor Superfamily Member 12a antibody
Anti-Fibroblast Growth Factor-Inducible Immediate-Early Response Protein 14 antibody
Anti-Fgf-Inducible 14 antibody
Anti-Tweak-Receptor antibody
Anti-Tweakr antibody
Anti-Cd Antigen Cd266 antibody
Anti-TNFRSF12A antibody
Anti-FN14 antibody

Information sourced from Uniprot.org

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