| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-Tumor Necrosis Factor Receptor Superfamily Member 10c (26-235) is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S5220RM |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TNFRSF10C |
| Gene ID: |
8794 |
| Uniprot ID: |
TR10C_HUMAN |
| Immunogen Region: |
26-235 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 26-235 of human DcR1/CD263 (NP_003832.3). |
| Immunogen Sequence: |
ATTARQEEVPQQTVAPQQQR HSFKGEECPAGSHRSEHTGA CNPCTEGVDYTNASNNEPSC FPCTVCKSDQKHKSSCTMTR DTVCQCKEGTFRNENSPEMC RKCSRCPSGEVQVSNCTSWD DIQCVEEFGANATVETPAAE ETMNTSPGTPAPAAEETMNT SPGTPAPAAEETMTTSPGTP APAAEETMTTSPGTPAPAAE ETMITSPGTP |
| Tissue Specificity | Higher expression in normal tissues than in tumor cell lines. Highly expressed in peripheral blood lymphocytes, spleen, skeletal muscle, placenta, lung and heart. |
| Post Translational Modifications | N-glycosylated and O-glycosylated. |
| Function | Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 10cAntagonist Decoy Receptor For Trail/Apo-2lDecoy Trail Receptor Without Death DomainDecoy Receptor 1Dcr1Lymphocyte Inhibitor Of TrailTnf-Related Apoptosis-Inducing Ligand Receptor 3Trail Receptor 3Trail-R3Trail Receptor Without An Intracellular DomainCd Antigen Cd263 |
| Database Links | Reactome: R-HSA-6803211 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 10c antibodyAnti-Antagonist Decoy Receptor For Trail/Apo-2l antibodyAnti-Decoy Trail Receptor Without Death Domain antibodyAnti-Decoy Receptor 1 antibodyAnti-Dcr1 antibodyAnti-Lymphocyte Inhibitor Of Trail antibodyAnti-Tnf-Related Apoptosis-Inducing Ligand Receptor 3 antibodyAnti-Trail Receptor 3 antibodyAnti-Trail-R3 antibodyAnti-Trail Receptor Without An Intracellular Domain antibodyAnti-Cd Antigen Cd263 antibodyAnti-TNFRSF10C antibodyAnti-DCR1 antibodyAnti-LIT antibodyAnti-TRAILR3 antibodyAnti-TRID antibodyAnti-UNQ321 antibodyAnti-PRO366 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
