| Short Description : | Rabbit polyclonal anti-Tumor necrosis factor alpha-induced protein 8-like protein 3 (15-45 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000ELISA 1:10000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TNFAIP8L3 |
| Gene ID: | 388121 |
| Uniprot ID: | TP8L3_HUMAN |
| Immunogen: | Synthesized peptide derived from the human TNFAIP8L3 at the amino acid range 15-45 |
| Immunogen Region: | 15-45 aa |
| Specificity: | This antibody detects endogenous levels of TNFAIP8L3 |
| Function | Acts as a lipid transfer protein. Preferentially captures and shuttles two lipid second messengers, i.e., phosphatidylinositol 4,5- bisphosphate and phosphatidylinositol 3,4,5-trisphosphate and increases their levels in the plasma membrane. Additionally, may also function as a lipid-presenting protein to enhance the activity of the PI3K-AKT and MEK-ERK pathways. May act as a regulator of tumorigenesis through its activation of phospholipid signaling. |
| Protein Name | Tumor Necrosis Factor Alpha-Induced Protein 8-Like Protein 3Tnf Alpha-Induced Protein 8-Like Protein 3Tnfaip8-Like Protein 3 |
| Database Links | Reactome: R-HSA-1483255 |
| Cellular Localisation | CytoplasmCell MembraneOn Pdgf ActivationTranslocates From Cytoplasm To Plasma Membrane |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Alpha-Induced Protein 8-Like Protein 3 antibodyAnti-Tnf Alpha-Induced Protein 8-Like Protein 3 antibodyAnti-Tnfaip8-Like Protein 3 antibodyAnti-TNFAIP8L3 antibodyAnti-TIPE3 antibody |
Information sourced from Uniprot.org
