Host: |
Rabbit |
Applications: |
WB/ELISA |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Tumor necrosis factor alpha-induced protein 8-like protein 3 (15-45 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000ELISA 1:10000-20000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
TNFAIP8L3 |
Gene ID: |
388121 |
Uniprot ID: |
TP8L3_HUMAN |
Immunogen Region: |
15-45 aa |
Specificity: |
This antibody detects endogenous levels of TNFAIP8L3 |
Immunogen: |
Synthesized peptide derived from the human TNFAIP8L3 at the amino acid range 15-45 |
Function | Acts as a lipid transfer protein. Preferentially captures and shuttles two lipid second messengers, i.e., phosphatidylinositol 4,5- bisphosphate and phosphatidylinositol 3,4,5-trisphosphate and increases their levels in the plasma membrane. Additionally, may also function as a lipid-presenting protein to enhance the activity of the PI3K-AKT and MEK-ERK pathways. May act as a regulator of tumorigenesis through its activation of phospholipid signaling. |
Protein Name | Tumor Necrosis Factor Alpha-Induced Protein 8-Like Protein 3Tnf Alpha-Induced Protein 8-Like Protein 3Tnfaip8-Like Protein 3 |
Database Links | Reactome: R-HSA-1483255 |
Cellular Localisation | CytoplasmCell MembraneOn Pdgf ActivationTranslocates From Cytoplasm To Plasma Membrane |
Alternative Antibody Names | Anti-Tumor Necrosis Factor Alpha-Induced Protein 8-Like Protein 3 antibodyAnti-Tnf Alpha-Induced Protein 8-Like Protein 3 antibodyAnti-Tnfaip8-Like Protein 3 antibodyAnti-TNFAIP8L3 antibodyAnti-TIPE3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance