• Western blot analysis of lysates from HUVEC cells, treated with PMA 125ng/ml 30', using TNAP1 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of the lysates from 293 cells using TNAP1 antibody.
  • Western blot analysis of various cells using TNF-IP 1 Polyclonal Antibody diluted at 1：500. Secondary antibody was diluted at 1:20000

Anti-TNFAIP1 antibody (71-120 aa) (STJ96049)

SKU:
STJ96049

£48.00 - £252.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (71-120 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TNFAIP1
Gene ID: 7126
Uniprot ID: BACD2_HUMAN
Immunogen Region: 71-120 aa
Specificity: TNF-IP 1 Polyclonal Antibody detects endogenous levels of TNF-IP 1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human TNAP1 at the amino acid range 71-120
Function Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(TNFAIP1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.
Protein Name Btb/Poz Domain-Containing Adapter For Cul3-Mediated Rhoa Degradation Protein 2
Hbacurd2
Btb/Poz Domain-Containing Protein Tnfaip1
Protein B12
Tumor Necrosis Factor - Alpha-Induced Protein 1 - Endothelial
Database Links Reactome: R-HSA-9696264
Reactome: R-HSA-9696270
Cellular Localisation Cytoplasm
Nucleus
Endosome
Colocalizes With Rhob In Endosomes
Alternative Antibody Names Anti-Btb/Poz Domain-Containing Adapter For Cul3-Mediated Rhoa Degradation Protein 2 antibody
Anti-Hbacurd2 antibody
Anti-Btb/Poz Domain-Containing Protein Tnfaip1 antibody
Anti-Protein B12 antibody
Anti-Tumor Necrosis Factor - Alpha-Induced Protein 1 - Endothelial antibody
Anti-TNFAIP1 antibody
Anti-BACURD2 antibody
Anti-EDP1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance