Anti-TNF RII/TNFRSF1B/CD120b antibody (23-258) (STJ11105379)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TNF RII/TNFRSF1B/CD120b (23-258) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:5000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | Tnfrsf1b |
| Gene ID | 21938 |
| Uniprot ID | TNR1B_MOUSE |
| Immunogen Region | 23-258 |
| Immunogen Sequence | VPAQVVLTPYKPEPGYECQI SQEYYDRKAQMCCAKCPPGQ YVKHFCNKTSDTVCADCEAS MYTQVWNQFRTCLSCSSSCT TDQVEIRACTKQQNRVCACE AGRYCALKTHSGSCRQCMRL SKCGPGFGVASSRAPNGNVL CKACAPGTFSDTTSSTDVCR PHRICSILAIPGNASTDAVC APESPTLSAIPRTLYVSQPE PTRSQPLDQEPGPSQTPSIL TSLGSTPIIEQSTKGG |
| Specificity | Recombinant Protein corresponding to a sequence within amino acids 23-258 of mouse TNF RII/TNFRSF1B/CD120b (NP_035740.2). |
Additional Info
| Function | Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 1bTumor Necrosis Factor Receptor 2Tnf-R2Tumor Necrosis Factor Receptor Type IiTnf-RiiTnfr-IiP75P80 Tnf-Alpha ReceptorCd Antigen Cd120b |
| Database Links | Reactome: R-MMU-5668541Reactome: -MMU-5669034Reactome: -MMU-6798695 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 1b antibodyAnti-Tumor Necrosis Factor Receptor 2 antibodyAnti-Tnf-R2 antibodyAnti-Tumor Necrosis Factor Receptor Type Ii antibodyAnti-Tnf-Rii antibodyAnti-Tnfr-Ii antibodyAnti-P75 antibodyAnti-P80 Tnf-Alpha Receptor antibodyAnti-Cd Antigen Cd120b antibodyAnti-Tnfrsf1b antibodyAnti-Tnfr-2 antibodyAnti-Tnfr2 antibody |
Information sourced from Uniprot.org