Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-TNF RII/TNFRSF1B/CD120b (23-258) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:1000-1:5000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
Tnfrsf1b |
Gene ID: |
21938 |
Uniprot ID: |
TNR1B_MOUSE |
Immunogen Region: |
23-258 |
Immunogen: |
Recombinant Protein corresponding to a sequence within amino acids 23-258 of mouse TNF RII/TNFRSF1B/CD120b (NP_035740.2). |
Immunogen Sequence: |
VPAQVVLTPYKPEPGYECQI SQEYYDRKAQMCCAKCPPGQ YVKHFCNKTSDTVCADCEAS MYTQVWNQFRTCLSCSSSCT TDQVEIRACTKQQNRVCACE AGRYCALKTHSGSCRQCMRL SKCGPGFGVASSRAPNGNVL CKACAPGTFSDTTSSTDVCR PHRICSILAIPGNASTDAVC APESPTLSAIPRTLYVSQPE PTRSQPLDQEPGPSQTPSIL TSLGSTPIIEQSTKGG |
Function | Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. |
Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 1bTumor Necrosis Factor Receptor 2Tnf-R2Tumor Necrosis Factor Receptor Type IiTnf-RiiTnfr-IiP75P80 Tnf-Alpha ReceptorCd Antigen Cd120b |
Database Links | Reactome: R-MMU-5668541Reactome: -MMU-5669034Reactome: -MMU-6798695 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 1b antibodyAnti-Tumor Necrosis Factor Receptor 2 antibodyAnti-Tnf-R2 antibodyAnti-Tumor Necrosis Factor Receptor Type Ii antibodyAnti-Tnf-Rii antibodyAnti-Tnfr-Ii antibodyAnti-P75 antibodyAnti-P80 Tnf-Alpha Receptor antibodyAnti-Cd Antigen Cd120b antibodyAnti-Tnfrsf1b antibodyAnti-Tnfr-2 antibodyAnti-Tnfr2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance