| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Transmembrane protease serine 6 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TMPRSS6 |
| Gene ID: | 164656 |
| Uniprot ID: | TMPS6_HUMAN |
| Specificity: | This antibody detects endogenous levels of TMPRSS6 at Human, Mouse |
| Immunogen: | Synthesized peptide derived from human TMPRSS6 |
| Function | Membrane-bound serine protease. Through the cleavage of cell surface HJV, a regulator of the expression of the iron absorption-regulating hormone hepicidin/HAMP, plays a role in iron homeostasis. |
| Protein Name | Transmembrane Protease Serine 6Matriptase-2 |
| Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1474228 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinThe ProcessedActivated Two-Chains Form Is Released In The Extracellular Space |
| Alternative Antibody Names | Anti-Transmembrane Protease Serine 6 antibodyAnti-Matriptase-2 antibodyAnti-TMPRSS6 antibodyAnti-UNQ354 antibodyAnti-PRO618 antibody |
Information sourced from Uniprot.org