| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TMPRSS11A |
| Gene ID: | 339967 |
| Uniprot ID: | TM11A_HUMAN |
| Immunogen Region: | 300-421 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 300-421 of human TMPRSS11A (NP_872412.3). |
| Immunogen Sequence: | SASFQPNLTVHITGFGALYY GGESQNDLREARVKIISDDV CKQPQVYGNDIKPGMFCAGY MEGIYDACRGDSGGPLVTRD LKDTWYLIGIVSWGDNCGQK DKPGVYTQVTYYRNWIASKT GI |
| Tissue Specificity | Expressed in esophagus, liver, colon and lung. Down-regulated in esophagus cancers. |
| Function | Probable serine protease which may play a role in cellular senescence. Overexpression inhibits cell growth and induce G1 cell cycle arrest. |
| Protein Name | Transmembrane Protease Serine 11aAirway Trypsin-Like Protease 1Epidermal Type-Ii Transmembrane Serine ProteaseEsophageal Cancer-Susceptibility Gene 1 Protein |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Transmembrane Protease Serine 11a antibodyAnti-Airway Trypsin-Like Protease 1 antibodyAnti-Epidermal Type-Ii Transmembrane Serine Protease antibodyAnti-Esophageal Cancer-Susceptibility Gene 1 Protein antibodyAnti-TMPRSS11A antibodyAnti-ECRG1 antibodyAnti-HATL1 antibodyAnti-HESP antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and CNPasease knockout (KO) HeLa cells, using [KO Validated] CNPase Rabbit polyclonal antibody (STJ119982) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/98767/382818/STJ119982_1__79726.1713151315.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and CNPasease knockout (KO) HeLa cells, using [KO Validated] CNPase Rabbit polyclonal antibody (STJ119982) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.")
