| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Lamina-associated polypeptide 2, isoforms beta/gamma is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TMPO |
| Gene ID: |
7112 |
| Uniprot ID: |
LAP2B_HUMAN |
| Specificity: |
LAP2B Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from part of the human protein |
| Post Translational Modifications | Mitosis-specific phosphorylation specifically abolishes its binding to lamin B and chromosomes. Citrullinated by PADI4. |
| Function | May help direct the assembly of the nuclear lamina and thereby help maintain the structural organization of the nuclear envelope. Possible receptor for attachment of lamin filaments to the inner nuclear membrane. May be involved in the control of initiation of DNA replication through its interaction with NAKAP95. Thymopoietin (TP) and Thymopentin (TP5) may play a role in T-cell development and function. TP5 is an immunomodulating pentapeptide. |
| Protein Name | Lamina-Associated Polypeptide 2 - Isoforms Beta/GammaThymopoietin - Isoforms Beta/GammaTp Beta/GammaThymopoietin-Related Peptide Isoforms Beta/GammaTprp Isoforms Beta/Gamma Cleaved Into - ThymopoietinTpSplenin - ThymopentinTp5 |
| Database Links | Reactome: R-HSA-2980766 P42167-1Reactome: R-HSA-2995383 P42167-1Reactome: R-HSA-4419969 P42167-1Reactome: R-HSA-8980692Reactome: R-HSA-9013106Reactome: R-HSA-9013148Reactome: R-HSA-9013149Reactome: R-HSA-9013404Reactome: R-HSA-9013405Reactome: R-HSA-9013408Reactome: R-HSA-9013409Reactome: R-HSA-9013423Reactome: R-HSA-9035034 |
| Cellular Localisation | Nucleus Inner MembraneSingle-Pass Type Ii Membrane ProteinTightly Associated With The Nuclear LaminaIsoform Zeta: Cytoplasm |
| Alternative Antibody Names | Anti-Lamina-Associated Polypeptide 2 - Isoforms Beta/Gamma antibodyAnti-Thymopoietin - Isoforms Beta/Gamma antibodyAnti-Tp Beta/Gamma antibodyAnti-Thymopoietin-Related Peptide Isoforms Beta/Gamma antibodyAnti-Tprp Isoforms Beta/Gamma Cleaved Into - Thymopoietin antibodyAnti-Tp antibodyAnti-Splenin - Thymopentin antibodyAnti-Tp5 antibodyAnti-TMPO antibodyAnti-LAP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
