| Short Description : | Rabbit polyclonal TMF1 (900-1000) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TMF1 |
| Gene ID: | 7110 |
| Uniprot ID: | TMF1_HUMAN |
| Immunogen Region: | 900-1000 |
| Immunogen Sequence: | MKVEQERKKAIFTQETIKEK ERKPFSVSSTPTMSRSSSIS GVDMAGLQTSFLSQDESHDH SFGPMPISANGSNLYDAVRM GAGSSIIENLQSQLKLREGE I |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 900-1000 of human TMF1 (NP_009045.2). |
| Post Translational Modifications | Phosphorylated by FER. |
| Function | Potential coactivator of the androgen receptor. Mediates STAT3 degradation. May play critical roles in two RAB6-dependent retrograde transport processes: one from endosomes to the Golgi and the other from the Golgi to the ER. This protein binds the HIV-1 TATA element and inhibits transcriptional activation by the TATA-binding protein (TBP). |
| Protein Name | Tata Element Modulatory FactorTmfAndrogen Receptor Coactivator 160 Kda ProteinAndrogen Receptor-Associated Protein Of 160 Kda |
| Database Links | Reactome: R-HSA-6811440 |
| Cellular Localisation | CytoplasmNucleusGolgi Apparatus MembraneConcentrated At The Budding Structures Localized At The Tips Of Cisternae |
| Alternative Antibody Names | Anti-Tata Element Modulatory Factor antibodyAnti-Tmf antibodyAnti-Androgen Receptor Coactivator 160 Kda Protein antibodyAnti-Androgen Receptor-Associated Protein Of 160 Kda antibodyAnti-TMF1 antibodyAnti-ARA160 antibody |
Information sourced from Uniprot.org
