| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Transmembrane protein 59-like (177-227 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TMEM59L |
| Gene ID: | 25789 |
| Uniprot ID: | TM59L_HUMAN |
| Immunogen Region: | 177-227 aa |
| Specificity: | This antibody detects endogenous levels of TM59L at Human/Mouse/Rat |
| Immunogen: | Synthesized peptide derived from the human TM59L at the amino acid range 177-227 |
| Function | Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding. |
| Protein Name | Transmembrane Protein 59-LikeBrain-Specific Membrane-Anchored Protein |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Transmembrane Protein 59-Like antibodyAnti-Brain-Specific Membrane-Anchored Protein antibodyAnti-TMEM59L antibodyAnti-BSMAP antibodyAnti-C19orf4 antibody |
Information sourced from Uniprot.org