• Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).

Anti-TMEM258 antibody (15-65 aa) (STJ196537)

SKU:
STJ196537

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Transmembrane protein 258 (15-65 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC-P 1:50-200
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TMEM258
Gene ID: 746
Uniprot ID: TM258_HUMAN
Immunogen Region: 15-65 aa
Specificity: This antibody detects endogenous levels of CK010 at Human/Mouse
Immunogen: Synthesized peptide derived from the human CK010 at the amino acid range 15-65
Function Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. Involved in ER homeostasis in the colonic epithelium.
Protein Name Transmembrane Protein 258
Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit Tmem258
Oligosaccharyl Transferase Subunit Tmem258
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Endoplasmic Reticulum
Cytoplasm
Alternative Antibody Names Anti-Transmembrane Protein 258 antibody
Anti-Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit Tmem258 antibody
Anti-Oligosaccharyl Transferase Subunit Tmem258 antibody
Anti-TMEM258 antibody
Anti-C11orf10 antibody
Anti-HSPC005 antibody

Information sourced from Uniprot.org

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