| Host: | Goat |
| Applications: | Pep-ELISA/WB/IHC |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-TMEM205 (142-151) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 22kDa band observed in Human Pancreas lysates (calculated MW of 21.2kDa according to NP_212133.1). Recommended concentration: 0.03-0.1µg/ml. Primary incubation was 1 hour.I |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | TMEM205 |
| Gene ID: | 374882 |
| Uniprot ID: | TM205_HUMAN |
| Immunogen Region: | 142-151 |
| Accession Number: | NP_212133.1 |
| Specificity: | Reported variants represent identical protein: NP_940938.1, NP_212133.1, NP_001138888.1. |
| Immunogen Sequence: | QLREKDPKYS |
| Function | In cancer cells, plays a role in resistance to the chemotherapeutic agent cisplatin. |
| Protein Name | Transmembrane Protein 205 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinLocated On Cell Surface MicrovilliIn Cancer CellsTransition In Subcellular Location From Cell Surface To Intracellular Regions Correlates The Progression Of Cisplatin Resistance |
| Alternative Antibody Names | Anti-Transmembrane Protein 205 antibodyAnti-TMEM205 antibodyAnti-UNQ501 antibodyAnti-PRO1018 antibody |
Information sourced from Uniprot.org
