| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TMEM165 (172-230) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TMEM165 |
| Gene ID: |
55858 |
| Uniprot ID: |
TM165_HUMAN |
| Immunogen Region: |
172-230 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 172-230 of human TMEM165 (NP_060945.2). |
| Immunogen Sequence: |
IRMLREGLKMSPDEGQEELE EVQAELKKKDEEFQRTKLLN GPGDVETGTSITVPQKKWL |
| Tissue Specificity | Ubiquitously expressed. |
| Function | Putative divalent cation:proton antiporter that exchanges calcium or manganese ions for protons across the Golgi membrane. Mediates the reversible transport of calcium or manganese to the Golgi lumen driven by the proton gradient and possibly the membrane potential generated by V-ATPase. Provides calcium or manganese cofactors to resident Golgi enzymes and contributes to the maintenance of an acidic luminal Golgi pH required for proper functioning of the secretory pathway. Promotes Ca(2+) storage within the Golgi lumen of the mammary epithelial cells to be then secreted into milk. The transport mechanism and stoichiometry remains to be elucidated. |
| Protein Name | Putative Divalent Cation/Proton Antiporter Tmem165Transmembrane Protein 165Transmembrane Protein Pt27Transmembrane Protein Tparl |
| Cellular Localisation | Golgi Apparatus MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Putative Divalent Cation/Proton Antiporter Tmem165 antibodyAnti-Transmembrane Protein 165 antibodyAnti-Transmembrane Protein Pt27 antibodyAnti-Transmembrane Protein Tparl antibodyAnti-TMEM165 antibodyAnti-TPARL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
