| Tissue Specificity | Ubiquitously expressed. |
| Function | Putative divalent cation:proton antiporter that exchanges calcium or manganese ions for protons across the Golgi membrane. Mediates the reversible transport of calcium or manganese to the Golgi lumen driven by the proton gradient and possibly the membrane potential generated by V-ATPase. Provides calcium or manganese cofactors to resident Golgi enzymes and contributes to the maintenance of an acidic luminal Golgi pH required for proper functioning of the secretory pathway. Promotes Ca(2+) storage within the Golgi lumen of the mammary epithelial cells to be then secreted into milk. The transport mechanism and stoichiometry remains to be elucidated. |
| Protein Name | Putative Divalent Cation/Proton Antiporter Tmem165Transmembrane Protein 165Transmembrane Protein Pt27Transmembrane Protein Tparl |
| Cellular Localisation | Golgi Apparatus MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Putative Divalent Cation/Proton Antiporter Tmem165 antibodyAnti-Transmembrane Protein 165 antibodyAnti-Transmembrane Protein Pt27 antibodyAnti-Transmembrane Protein Tparl antibodyAnti-TMEM165 antibodyAnti-TPARL antibody |
Information sourced from Uniprot.org
