Anti-TMEFF2 antibody [SAA1493] (STJA0019921)

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STJA0019921
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Host: Mouse
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Mouse monoclonal antibody anti-Tomoregulin-2 is suitable for use in ELISA research applications.
Clonality : Monoclonal
Clone ID : SAA1493
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Concentration: 1 mg/mL
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol: TMEFF2
Gene ID: 23671
Uniprot ID: TEFF2_HUMAN
Post Translational Modifications O-glycosylated.contains chondroitin sulfate glycosaminoglycans. A soluble form (TMEFF2-ECD) is produced by proteolytic shedding. This shedding can be induced by phorbol ester or pro-inflammatory cytokines such as TNFalpha, and is mediated by ADAM17.
Function May be a survival factor for hippocampal and mesencephalic neurons. The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation.
Protein Name Tomoregulin-2
Tr-2
Hyperplastic Polyposis Protein 1
Transmembrane Protein With Egf-Like And Two Follistatin-Like Domains
Cellular Localisation Isoform 1: Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Membrane
Isoform 3: Secreted
Alternative Antibody Names Anti-Tomoregulin-2 antibody
Anti-Tr-2 antibody
Anti-Hyperplastic Polyposis Protein 1 antibody
Anti-Transmembrane Protein With Egf-Like And Two Follistatin-Like Domains antibody
Anti-TMEFF2 antibody
Anti-HPP1 antibody
Anti-TENB2 antibody
Anti-TPEF antibody
Anti-UNQ178 antibody
Anti-PRO204 antibody

Information sourced from Uniprot.org