| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TMED3 |
| Gene ID: | 23423 |
| Uniprot ID: | TMED3_HUMAN |
| Immunogen Region: | 24-180 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-180 of human TMED3 (NP_031390.1). |
| Immunogen Sequence: | PCGAELTFELPDNAKQCFHE EVEQGVKFSLDYQVITGGHY DVDCYVEDPQGNTIYRETKK QYDSFTYRAEVKGVYQFCFS NEFSTFSHKTVYFDFQVGDE PPILPDMGNRVTALTQMESA CVTIHEALKTVIDSQTHYRL REAQDRARAEDLNSRVS |
| Function | Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network. |
| Protein Name | Transmembrane Emp24 Domain-Containing Protein 3Membrane Protein P24bP24 Family Protein Gamma-4P24gamma4P26 |
| Database Links | Reactome: R-HSA-6807878Reactome: R-HSA-6811434 |
| Cellular Localisation | Endoplasmic Reticulum-Golgi Intermediate Compartment MembraneSingle-Pass Type I Membrane ProteinGolgi ApparatusCis-Golgi Network MembraneGolgi Stack MembraneEndoplasmic Reticulum MembraneCytoplasmic VesicleCopi-Coated Vesicle MembraneProbably Cycles Between Compartments Of The Early Secretatory Pathway |
| Alternative Antibody Names | Anti-Transmembrane Emp24 Domain-Containing Protein 3 antibodyAnti-Membrane Protein P24b antibodyAnti-P24 Family Protein Gamma-4 antibodyAnti-P24gamma4 antibodyAnti-P26 antibodyAnti-TMED3 antibodyAnti-C15orf22 antibodyAnti-UNQ5357 antibodyAnti-PRO1078 antibody |
Information sourced from Uniprot.org