Anti-TIP30/HTATIP2 antibody (1-242aa) [AT5D6] (STJA0041818)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2ak
ImmunogenRecombinant human HTATIP2 (1-242aa) purified from E. coli
General Information
| Short Description | Mouse monoclonal anti-TIP30/HTATIP2 (1-242aa) for use in ELISA, WB, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB/ICC/IF |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | AT5D6 |
| Isotype | IgG2ak |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | By protein-A affinity chromatography |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HTATIP2 |
| Gene ID | 10553 |
| Uniprot ID | HTAI2_HUMAN |
| Accession Number | AAH15358 |
| Immunogen | Recombinant human HTATIP2 (1-242aa) purified from E. coli |
| Immunogen Region | 1-242aa |
Additional Info
| Tissue Specificity | High levels in liver, lung, skeletal muscle, pancreas and placenta. Moderate levels in heart and kidney. Low levels in brain. Not expressed or low levels in variant small cell lung carcinomas, 33% of hepatocellular carcinomas and neuroblastomas. Levels are reduced in the heart of patients with hypertrophic cardiomyopathy and failing hearts. |
| Function | Represses translation by preventing reactivation of elongation factor eEF1A. May also inhibit nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. Has additionally been proposed to act as a redox sensor involved in cellular oxidative stress surveillance. |
| Protein Name | Protein Htatip230 Kda Hiv-1 Tat-Interacting ProteinHiv-1 Tat-Interactive Protein 2 |
| Database Links | |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Protein Htatip2 antibodyAnti-30 Kda Hiv-1 Tat-Interacting Protein antibodyAnti-Hiv-1 Tat-Interactive Protein 2 antibodyAnti-HTATIP2 antibodyAnti-CC3 antibodyAnti-TIP30 antibody |
Information sourced from Uniprot.org