Anti-TIMP2 antibody (100-200) (STJ118867)

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STJ118867
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Host: Rabbit
Applications: WB/IHC-P/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
IHC-P:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TIMP2
Gene ID: 7077
Uniprot ID: TIMP2_HUMAN
Immunogen Region: 100-200
Specificity: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human TIMP2 (NP_003246.1).
Immunogen Sequence: VSLDVGGKKEYLIAGKAEGD GKMHITLCDFIVPWDTLSTT QKKSLNHRYQMGCECKITRC PMIPCYISSPDECLWMDWVT EKNINGHQAKFFACIKRSDG S
Post Translational Modifications The activity of TIMP2 is dependent on the presence of disulfide bonds.
Function Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.
Protein Name Metalloproteinase Inhibitor 2
Csc-21k
Tissue Inhibitor Of Metalloproteinases 2
Timp-2
Database Links Reactome: R-HSA-1592389
Reactome: R-HSA-6798695
Reactome: R-HSA-9839383
Cellular Localisation Secreted
Alternative Antibody Names Anti-Metalloproteinase Inhibitor 2 antibody
Anti-Csc-21k antibody
Anti-Tissue Inhibitor Of Metalloproteinases 2 antibody
Anti-Timp-2 antibody
Anti-TIMP2 antibody

Information sourced from Uniprot.org