Anti-TIMM50 antibody [R03-8P9] (STJA0037125)

SKU:
STJA0037125
€160.20 - €337.80
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Host: Rabbit
Applications: WB/IHC-P
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-TIMM50 for use in WB and IHC-P in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : R03-8P9
Conjugation: Unconjugated
Isotype: IgG
Formulation: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification: Affinity Purified
Dilution Range: WB 1:500-1:1000
IHC 1:50-1:100
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: TIMM50
Gene ID: 92609
Uniprot ID: TIM50_HUMAN
Immunogen: A synthesized peptide derived from human TIMM50
Tissue Specificity Widely expressed. Expressed at higher level in brain, kidney and liver (at protein level).
Function Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro.however such activity may not be relevant in vivo. Isoform 2: May participate in the release of snRNPs and SMN from the Cajal body.
Protein Name Mitochondrial Import Inner Membrane Translocase Subunit Tim50
Database Links Reactome: R-HSA-1268020
Cellular Localisation Mitochondrion Inner Membrane
Single-Pass Membrane Protein
Isoform 2: Nucleus Speckle
Nuclear And Enriched In Speckles With Snrnps
Alternative Antibody Names Anti-Mitochondrial Import Inner Membrane Translocase Subunit Tim50 antibody
Anti-TIMM50 antibody
Anti-TIM50 antibody
Anti-PRO1512 antibody

Information sourced from Uniprot.org