| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Mitochondrial import inner membrane translocase subunit TIM50 (109-159 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TIMM50 |
| Gene ID: | 92609 |
| Uniprot ID: | TIM50_HUMAN |
| Immunogen Region: | 109-159 aa |
| Specificity: | This antibody detects endogenous levels of TIM50 at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human TIM50 at the amino acid range 109-159 |
| Function | Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro.however such activity may not be relevant in vivo. Isoform 2: May participate in the release of snRNPs and SMN from the Cajal body. |
| Protein Name | Mitochondrial Import Inner Membrane Translocase Subunit Tim50 |
| Database Links | Reactome: R-HSA-1268020 |
| Cellular Localisation | Mitochondrion Inner MembraneSingle-Pass Membrane ProteinIsoform 2: Nucleus SpeckleNuclear And Enriched In Speckles With Snrnps |
| Alternative Antibody Names | Anti-Mitochondrial Import Inner Membrane Translocase Subunit Tim50 antibodyAnti-TIMM50 antibodyAnti-TIM50 antibodyAnti-PRO1512 antibody |
Information sourced from Uniprot.org