Host: | Goat |
Applications: | Pep-ELISA/WB/IHC |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Goat polyclonal antibody anti-thyroid peroxidase (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: | 0.5 mg/mL |
Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 110kDa band observed in Human Thyroid Gland lysates (calculated MW of 103kDa according to NP_000538.3). Recommended concentration: 0.1-0.3µg/ml.IHC: In paraffin embedded Hu |
Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: | TPO |
Gene ID: | 7173 |
Uniprot ID: | PERT_HUMAN |
Immunogen Region: | C-Term |
Accession Number: | NP_000538.3; NP_783650.1; NP_783652.1; NP_783653.1 |
Specificity: | This antibody is expected to recognize all reported isoforms (NP_000538.3; NP_783650.1; NP_783652.1; NP_783653.1). Reported variants represent identical protein: NP_000538.3, NP_001193673.1 Reported variants represent identical protein: NP_783650.1, |
Immunogen Sequence: | ELRCGKHQAVGTSPQ |
Function | Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4). |
Protein Name | Thyroid PeroxidaseTpo |
Database Links | Reactome: R-HSA-209968 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinIsoform 3: Cell Surface |
Alternative Antibody Names | Anti-Thyroid Peroxidase antibodyAnti-Tpo antibodyAnti-TPO antibody |
Information sourced from Uniprot.org