Anti-Thyroid Hormone Receptor alpha antibody [R07-3J8] (STJA0037228)

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STJA0037228
$184.23 - $388.47
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-Thyroid Hormone Receptor alpha for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : R07-3J8
Conjugation: Unconjugated
Isotype: IgG
Formulation: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification: Affinity Purified
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: THRA
Gene ID: 7067
Uniprot ID: THA_HUMAN
Immunogen: A synthesized peptide derived from human THRA
Function Isoform Alpha-1: Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine. Isoform Alpha-2: Does not bind thyroid hormone and functions as a weak dominant negative inhibitor of thyroid hormone action.
Protein Name Thyroid Hormone Receptor Alpha
Nuclear Receptor Subfamily 1 Group A Member 1
V-Erba-Related Protein 7
Ear-7
C-Erba-1
C-Erba-Alpha
Database Links Reactome: R-HSA-383280
Reactome: R-HSA-4090294 P10827-2
Cellular Localisation Nucleus
Isoform Alpha-2: Cytoplasm
When Overexpressed Found In The Cytoplasm Where It Colocalizes With Tacc1
Alternative Antibody Names Anti-Thyroid Hormone Receptor Alpha antibody
Anti-Nuclear Receptor Subfamily 1 Group A Member 1 antibody
Anti-V-Erba-Related Protein 7 antibody
Anti-Ear-7 antibody
Anti-C-Erba-1 antibody
Anti-C-Erba-Alpha antibody
Anti-THRA antibody
Anti-EAR7 antibody
Anti-ERBA1 antibody
Anti-NR1A1 antibody
Anti-THRA1 antibody
Anti-THRA2 antibody

Information sourced from Uniprot.org

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