• Western blot of rat hippocampal lysate showing specific immunolabeling of the ~50 kDa TR-Alpha 1 and the ~58 kDa TR-Alpha 2 protein.

Anti-Thyroid Hormone Receptor Alpha 1/2 antibody (N-Term) [2103] (STJA0003800)

SKU:
STJA0003800-100

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Host: Mouse
Applications: WB
Reactivity: Human/Rat/Canine/Mouse/Non-Human Primates
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Thyroid Hormone Receptor alpha 1/2 (N-Term) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: 2103
Conjugation: Unconjugated
Isotype: IgG1
Formulation: 100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol.
Purification: This antibody was protein g purified culture from supernatant.
Dilution Range: WB 1:1000
IHC
ICC
IP
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: THRA
Gene ID: 7067
Uniprot ID: THA_HUMAN
Immunogen Region: N-Term
Immunogen: Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH.
Function Isoform Alpha-1: Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine. Isoform Alpha-2: Does not bind thyroid hormone and functions as a weak dominant negative inhibitor of thyroid hormone action.
Protein Name Thyroid Hormone Receptor Alpha
Nuclear Receptor Subfamily 1 Group A Member 1
V-Erba-Related Protein 7
Ear-7
C-Erba-1
C-Erba-Alpha
Database Links Reactome: R-HSA-383280
Reactome: R-HSA-4090294 P10827-2
Cellular Localisation Nucleus
Isoform Alpha-2: Cytoplasm
When Overexpressed Found In The Cytoplasm Where It Colocalizes With Tacc1
Alternative Antibody Names Anti-Thyroid Hormone Receptor Alpha antibody
Anti-Nuclear Receptor Subfamily 1 Group A Member 1 antibody
Anti-V-Erba-Related Protein 7 antibody
Anti-Ear-7 antibody
Anti-C-Erba-1 antibody
Anti-C-Erba-Alpha antibody
Anti-THRA antibody
Anti-EAR7 antibody
Anti-ERBA1 antibody
Anti-NR1A1 antibody
Anti-THRA1 antibody
Anti-THRA2 antibody

Information sourced from Uniprot.org

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