| Host: | Mouse |
| Applications: | IHC-P |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-Thymidylate Synthase for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | ZN227 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2a |
| Formulation: | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Purification: | Affinity Chromatography |
| Concentration: | 0.5-1.0 mg/mL |
| Dilution Range: | IHC 1:50-1:100 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | TYMS |
| Gene ID: | 7298 |
| Uniprot ID: | TYSY_HUMAN |
| Immunogen: | Full length human recombinant protein of human TYMS (TS) (NP_001062) produced in E.coli. |
| Function | Catalyzes the reductive methylation of 2'-deoxyuridine 5'-monophosphate (dUMP) to thymidine 5'-monophosphate (dTMP), using the cosubstrate, 5,10- methylenetetrahydrofolate (CH2H4folate) as a 1-carbon donor and reductant and contributes to the de novo mitochondrial thymidylate biosynthesis pathway. |
| Protein Name | Thymidylate SynthaseTsTsase |
| Database Links | Reactome: R-HSA-499943Reactome: R-HSA-69205 |
| Cellular Localisation | NucleusCytoplasmMitochondrionMitochondrion MatrixMitochondrion Inner Membrane |
| Alternative Antibody Names | Anti-Thymidylate Synthase antibodyAnti-Ts antibodyAnti-Tsase antibodyAnti-TYMS antibodyAnti-TS antibodyAnti-OK antibodyAnti-SW-cl.29 antibody |
Information sourced from Uniprot.org
